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CAS No 123441-03-2 , [3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate Search by region : Canada

  • Name: [3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate
  • Synonyms: AC1L2U92; 123441-03-2; CHEMBL636;ENA 713 free base; CHEBI:8874;[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate; Rivastigmine [USAN:INN]; UNII-PKI06M3IW0; BIDD:GT0316;
  • CAS Registry Number:
  • Flash Point: 145°C
  • Boiling Point: 316.2°Cat760mmHg
  • Density: 1.038g/cm3
  • Refractive index: 1.518
  • Flash Point: 145°C
  • Molecular Weight: 250.33668
  • InchiKey: XSVMFMHYUFZWBK-NSHDSACASA-N
  • InChI: InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-
    11H,6H2,1-5H3/t11-/m0/s1
  • Molecular Formula: C14H22N2O2
  • Molecular Structure:CAS No:123441-03-2 [3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate

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123441-03-2 RIVASTIGMINE-D3 HYDROCHLORIDE

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References of [3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate
Title: Rivastigmine
CAS Registry Number: 123441-03-2
CAS Name: Ethylmethylcarbamic acid 3-[(1S)-1-(dimethylamino)ethyl]phenyl ester
Synonyms: (S)-N-ethyl-3-[(1-dimethylamino)ethyl]-N-methylphenylcarbamate
Molecular Formula: C14H22N2O2
Molecular Weight: 250.34
Percent Composition: C 67.17%, H 8.86%, N 11.19%, O 12.78%
Literature References: Brain selective acetylcholinesterase inhibitor. Prepn: A. Enz, DE 3805744; idem, US 5602176 (1988, 1997 both to Sandoz); and activity: R. Amstutz et al., Helv. Chim. Acta 73, 739 (1990). Pharmacology: A. Enz et al., Prog. Brain Res. 98, 431 (1993). Clinical trial in Alzheimer's disease: M. R?sler et al., Br. Med. J. 318, 633 (1999).
Properties: [a]D20 -32.1° (c = 5 in ethanol).
Optical Rotation: [a]D20 -32.1° (c = 5 in ethanol)
 
Derivative Type: Hydrogen tartrate
CAS Registry Number: 129101-54-8
Manufacturers' Codes: ENA-713; SDZ-ENA-713; SDZ-212-713
Trademarks: Exelon (Novartis)
Molecular Formula: C14H22N2O2.C4H6O6
Molecular Weight: 400.42
Percent Composition: C 53.99%, H 7.05%, N 7.00%, O 31.97%
Properties: Crystals from ethanol, mp 123-125°. [a]D20 +4.7° (c = 5 in ethanol).
Melting point: mp 123-125°
Optical Rotation: [a]D20 +4.7° (c = 5 in ethanol)
 
Therap-Cat: Nootropic.
Keywords: Cholinesterase Inhibitor; Nootropic.