Title: Cetylpyridinium Chloride
CAS Registry Number: 123-03-5
CAS Name: 1-Hexadecylpyridinium chloride
Trademarks: Ceepryn (J. B. Williams); Medilave (Farillon); Merocet (HMR); Pristacin; Pyrisept
Molecular Formula: C21H38ClN
Molecular Weight: 339.99
Percent Composition: C 74.19%, H 11.27%, Cl 10.43%, N 4.12%
Literature References: Pharmacology and toxicology:
J. Pharmacol. Exp. Ther. 74, 401 (1942). Review of early literature: C. L. Huyck,
Am. J. Pharm. 116, 50 (1944). Toxicity data: J. W. Nelson, S. C. Lyster,
J. Am. Pharm. Assoc. 35, 89 (1946).
Derivative Type: Monohydrate
CAS Registry Number: 6004-24-6
Trademarks: Dobendan (Cassella-med); Halset (Strohschein)
Properties: White powder, mp 77-83°. Freely sol in water, alcohol, chloroform; very slightly sol in benzene, ether. pH (1% aq soln): 6.0 to 7.0. Surface tension (25°): 43 dyn/cm (0.1% aq soln); 41 dyn/cm (1.0%); 38 dyn/cm (10%). LD50 in rats (mg/kg): 250 s.c.; 6 i.p.; 30 i.v.; 200 orally (Nelson, Lyster).
Melting point: mp 77-83°
Toxicity data: LD50 in rats (mg/kg): 250 s.c.; 6 i.p.; 30 i.v.; 200 orally (Nelson, Lyster)
Use: Pharmaceutic aid (preservative).
Therap-Cat: Antiseptic; disinfectant.
Therap-Cat-Vet: Topical antiseptic; disinfectant.
Keywords: Antiseptic/Disinfectant; Quaternary Ammonium Compounds.