Home > Name List By 5 > 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1, 3-thiazolidine-2,4-dione China

CAS No 122320-73-4 , 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,
3-thiazolidine-2,4-dione Search by region : China

  • Name: 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,
    3-thiazolidine-2,4-dione
  • Synonyms: BRL49653; Rosiglizole; Brl-49653; rosiglitazonum; Rosigliazone maleate;5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,
    3-thiazolidine-2,4-dione; 122320-73-4; rosiglitazona;Avandia; Brl 49653;
  • CAS Registry Number:
  • Melting Point: 153-155 C
  • Flash Point: 307.6°C
  • Boiling Point: 585°Cat760mmHg
  • Density: 1.315g/cm3
  • Safety Statements: S26;S37/39;
  • Hazard Symbols: Xi
  • Flash Point: 307.6°C
  • Molecular Weight: 357.42676
  • InchiKey: YASAKCUCGLMORW-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)
    12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23)
  • Risk Statements: 36/38
  • Molecular Formula: C18H19N3O3S
  • Molecular Structure:CAS No:122320-73-4 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,<br />3-thiazolidine-2,4-dione

Related products

Select to

122320-73-4 Rosiglitazone

Contact Supplier

122320-73-4 Rosiglitazone

  • Synonym: 5-(4-[2-(METHYL-PYRIDIN-2-YL-AMINO)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE;5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione;AVANDIA;ROSIGLITAZONE;ROSIGLITAZONE HCL;Rosiglitazone free base;Rosiglitazone and its ...
  • China Hubei Yuancheng Gongchuang Technology Co.,Ltd [Manufacturer]
  • Tel: 86-027-50756226
  • Address: No.496,Zhongshan Road, Wuhan, Hubei, China wuhan,HubeiChina
Contact Supplier

122320-73-4 Rosiglitazone

  • Product Name: 5-(4-[2-(METHYL-PYRIDIN-2-YL-AMINO)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE;5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione;AVANDIA;ROSIGLITAZONE;ROSIGLITAZONE HCL;Rosiglitazone free base;Rosiglitazone and...
  • China Shanghai Send Pharmaceutical Technology Co., Ltd [Manufacturer]
  • Tel: 86-21-50266790
  • Fax: 86-21-50266790
  • Address: No.300 Chuantu Road Pudong District Shanghai,China Shanghai,ShanghaiChina
Contact Supplier

122320-73-4 Rosiglitazone

Contact Supplier

122320-73-4 Rosiglitazone

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
Contact Supplier

122320-73-4 ROSIGLITRAZONE

  • China Xingcheng Chempharm Co., Ltd [Manufacturer]
  • Tel: +86-576-88525005/ +86-576-88886292
  • Fax: +86-576-88225056
  • Address: B Area, 10F, Yaoda Mansion, 289, Shifu Road, Taizhou, Zhejiang, China 318000 null,nullChina
Contact Supplier

122320-73-4 Rosiglitazone

  • China Wuxi Mizat Chemical Technology Co., Ltd. [Manufacturer]
  • Tel: +86-510-86106900/ +86-510-86125752
  • Fax: +86-510-86125752
  • Address: No.205,zhencheng Road,
    HI-TECT District,
    Wuxi, Jiangsu,China null,nullChina
Contact Supplier

122320-73-4 Rosiglitazone

  • Rosiglitazone 122320-73-4 Rotigotine 125572-93-2 Sevelamer Hydrochloride 152751-57-0 sitagliptin phosphate monohydrate 654671-77-9 Solifenacin succinate 242478-38-2 Sorafenib Tosylate(TINIBS) 4750207-59-1 Sunitinib malate(TINIBS) 341031-54-7 Streptoz...
  • China Wuhan Sunrise Technology development company limited [Manufacturers]
  • Tel: +86-27-83314682
  • Fax: 86 27 83314682
  • Address: Floor 5, Wunan Road No.15, Haixia Investment Zone, Wujiashan Wuhan, China Wuhan,HubeiChina
Contact Supplier

122320-73-4 Rosiglitazone

Contact Supplier

122320-73-4 Rosiglitazone

  • China Goly Chemical Co., Ltd. [Manufacturers]
  • Tel: +86-(632)-6163187
  • Fax: +86-(632)-5100028
  • Address: Room No.6.Building21 LongXingBeiLi,ShiZhong, ZaoZhua, ShanDong 277102, ZaoZhuang,ShanDongChina
Contact Supplier

Select to

1/7
1 2 3 4 5 6 7 Next
References of 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,
3-thiazolidine-2,4-dione
Title: Rosiglitazone
CAS Registry Number: 122320-73-4
CAS Name: 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
Synonyms: 5-[4-[2-[N-methyl-N-(2-pyridinyl)amino]ethoxy]benzyl]-2,4-thiazolidinedione
Manufacturers' Codes: BRL-49653
Molecular Formula: C18H19N3O3S
Molecular Weight: 357.43
Percent Composition: C 60.49%, H 5.36%, N 11.76%, O 13.43%, S 8.97%
Literature References: Insulin sensitizer; binds to peroxisome proliferator activated receptor gamma (PPAR-g). Prepn: R. M. Hindley, EP 306228; idem, US 5002953 (1989, 1991 both to Beecham); B. C. C. Cantello et al., J. Med. Chem. 37, 3977 (1994). Pharmacology: N. D. Oakes et al., Diabetes 43, 1203 (1994). Binding study: D. E. Mais et al., Med. Chem. Res. 7, 325 (1997). Clinical pharmacokinetics and bioavailability: M. I. Freed et al., Eur. J. Clin. Pharmacol. 55, 53 (1999). Review of pharmacology and clinical experience: J. A. Barman Balfour, G. L. Plosker, Drugs 57, 921-930 (1999).
Properties: Colorless crystals from methanol, mp 153-155°.
Melting point: mp 153-155°
 
Derivative Type: Maleate
CAS Registry Number: 155141-29-0
Manufacturers' Codes: BRL-49653c
Trademarks: Avandia (GSK)
Molecular Formula: C18H19N3O3S.C4H4O4
Molecular Weight: 473.50
Percent Composition: C 55.80%, H 4.90%, N 8.87%, O 23.65%, S 6.77%
Properties: White to off-white solid, mp 122-123°. pKa 6.1; 6.8. Readily sol in ethanol and in buffered aq soln with pH of 2.3; soly decreases with increasing pH in the physiological range.
Melting point: mp 122-123°
pKa: pKa 6.1; 6.8
 
Therap-Cat: Antidiabetic.
Keywords: Insulin Sensitizer; Antidiabetic; Thiazolidinediones.