CAS No 1217486-61-7 , (2S)-1-N-[4-methyl-5-[2-(1,1,
1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,
3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide

Name: (2S)-1-N-[4-methyl-5-[2-(1,1,
1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,
3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide
Synonyms: BYL-719; 1217486-61-7; QCR-1; cc-697; BYL 719; BYL719; CS-0663; HY-15244; cas:1217486-61-7;BYL-719; BYL-719|1217486-61-7|BYL719
CAS Registry Number:1217486-61-7
Density: 1.391
Molecular Weight: 441.47049
InchiKey: STUWGJZDJHPWGZ-LBPRGKRZSA-N
InChI: InChI=1S/C19H22F3N5O2S/c1-10-14(11-6-7-24-13(9-11)18(2,3)19(20,
21)22)30-16(25-10)26-17(29)27-8-4-5-12(27)15(23)28/h6-7,9,12H,4-5,8H2,
1-3H3,(H2,23,28)(H,25,26,29)/t12-/m0/s1
Molecular Formula: C₁₉H₂₂F₃N₅O₂S
Molecular Structure:

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BYL-719 BYL719 is a potent and selective PI3Kα inhibitor with IC50 of 5 nM, ;liitle or no effect on PI3Kβ/γ/δ. IC50 value: 5 nM [1] Target: PI3Kα in vitro: BYL719 inhibits the proliferation of breast cancer cell lines harboring PIK3CA mutations,...
MedChemexpress LLC [Manufacturer]
Tel: 609-228-6898
Fax: --
Address: 18 Wilkinson Way, Princeton, NJ 08540, USA Princeton,New JerseyUnited States

BYL-719 is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL-719 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibit...
ChemScene, LLC [Manufacturer]
Tel: 732-484-9848
Fax: --
Address: 11 Deer Park Drive, Suite 102D, Monmouth Junction, NJ 08852 Monmouth Junction,New JerseyUnited States

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CAS No 1217486-61-7 , (2S)-1-N-[4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl]pyrrolidine-1,2-dicarboxamide