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CAS No 119386-96-8 , Benzenebutanamine,4-fluoro-b-(fluoromethylene)-, (bE)-

  • Name: Benzenebutanamine,4-fluoro-b-(fluoromethylene)-, (bE)-
  • Synonyms: Mofegiline;Benzenebutanamine,4-fluoro-b-(fluoromethylene)-, (bE)-;(E)-2-(Fluoromethylene)-4-(4-fluorophenyl)butylamine;(E)-2-(Fluoromethylene)-4-(p-fluorophenyl)butylamine;Benzenebutanamine,4-fluoro-b-(fluoromethylene)-, (E)-; MDL 72974;
  • CAS Registry Number:
  • Flash Point: 165.3°C
  • Boiling Point: 288.6°Cat760mmHg
  • Density: 1.104g/cm3
  • Refractive index: 1.508
  • Flash Point: 165.3°C
  • Molecular Weight: 0
  • InChI: InChI=1/C11H13F2N/c12-7-10(8-14)2-1-9-3-5-11(13)6-4-9/h3-7H,1-2,8,14H2/b10-7-
  • Molecular Formula: C11H13 F2 N
  • Molecular Structure:CAS No:119386-96-8 Benzenebutanamine,4-fluoro-b-(fluoromethylene)-, (bE)-

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References of Benzenebutanamine,4-fluoro-b-(fluoromethylene)-, (bE)-
Title: Mofegiline
CAS Registry Number: 119386-96-8
CAS Name: (bE)-4-Fluoro-b-(fluoromethylene)benzenebutanamine
Synonyms: (E)-2-(fluoromethylene)-4-(p-fluorophenyl)butylamine; (E)-2-(4-fluorophenethyl)-3-fluoroallylamine
Molecular Formula: C11H13F2N
Molecular Weight: 197.22
Percent Composition: C 66.99%, H 6.64%, F 19.27%, N 7.10%
Literature References: Irreversible monoamine oxidase-B (MAO-B) inhibitor. Prepn: I. A. McDonald, M. G. Palfreyman, EP 295604 (1988 to Merrell Dow). GC-MS determn in plasma and urine: B. D. Dulery et al., J. Chromatogr. 571, 241 (1991). Pharmacokinetics: eidem et al., Arzneim.-Forsch. 43, 297 (1993). Metabolism: J. Dow et al., Drug Metab. Dispos. 22, 738 (1994). Clinical pharmacology: C. Hinze et al., J. Neural Transm. Suppl. 41, 371-375 (1994). Clinical evaluation in Parkinson's disease: V. V. Myllyl? et al., Adv. Neurol. 60, 676 (1993).
 
Derivative Type: Hydrochloride
CAS Registry Number: 120635-25-8
Manufacturers' Codes: MDL-72974A
Molecular Formula: C11H13F2N.HCl
Molecular Weight: 233.69
Percent Composition: C 56.54%, H 6.04%, F 16.26%, N 5.99%, Cl 15.17%
Properties: Colorless plates, mp 131°.
Melting point: mp 131°
 
Therap-Cat: Antiparkinsonian.
Keywords: Antiparkinsonian; Monoamine Oxidase Inhibitor.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.