CAS No 119-48-2 , 4-Morpholinecarboxamide,N,N'-1,2-ethanediylbis[N-butyl-

Name: 4-Morpholinecarboxamide,N,N'-1,2-ethanediylbis[N-butyl-
Synonyms: Amipan T;4-Morpholinecarboxamide,N,N'-1,2-ethanediylbis[N-butyl-; TH1064; Atmurin; Respiron;4-Morpholinecarboxamide,N,N'-ethylenebis[N-butyl- (6CI,7CI,8CI); Theraleptique;N,N'-Ethylenebis[N-butyl-4-morpholinecarboxamide]; Prontodin; Theraptique; Dimorpholamine; 1064 TH; Therapline;
CAS Registry Number:119-48-2
Flash Point: 299.3°C
Boiling Point: 571.3°Cat760mmHg
Density: 1.114g/cm³
Refractive index: 1.516
Safety Statements: Poison by ingestion, intraperitoneal, intravenous, intramuscular, and subcutaneous routes. An analeptic agent (stimulant). When heated to decomposition it emits toxic fumes of NOx. See also AMINES.
Flash Point: 299.3°C
EINECS: 204-328-7
Molecular Weight: 398.54012
InChI: InChI=1/C20H38N4O4/c1-3-5-7-21(19(25)23-11-15-27-16-12-23)9-10-22(8-6-4-2)20(26)24-13-17-28-18-14-24/h3-18H2,1-2H3
Molecular Formula: C20H38N4O4
Molecular Structure:

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References of 4-Morpholinecarboxamide,N,N'-1,2-ethanediylbis[N-butyl-

Title: Dimorpholamine
CAS Registry Number: 119-48-2
CAS Name: N,N￠-1,2-Ethanediylbis[N-butyl-4-morpholinecarboxamide]
Synonyms: N,N￠-dibutyl-N,N￠-dicarboxymorpholideethylenediamine; N,N￠-dibutyl-N,N￠-dicarboxyethylene diaminemorpholide
Manufacturers' Codes: TH-1064
Trademarks: Amipan T; Théraleptique; Theraptique
Molecular Formula: C20H38N4O4
Molecular Weight: 398.54
Percent Composition: C 60.27%, H 9.61%, N 14.06%, O 16.06%
Literature References: Prepn: Boon, J. Chem. Soc. 1947, 307; idem, US 2398283 and US 2409829 (both 1946 to I.C.I.). Toxicity data: Y. Kasé et al., Arch. Int. Pharmacodyn. Ther. 163, 133 (1966).
Properties: Crystals from petr ether, mp 41-42°. bp0.4 229°. Solubility in water: 50%. LD50 in mice (mg/10 g): 0.54 i.v.; 0.80 i.p.; 1.04 s.c.; 3.80 orally (Kasé).
Melting point: mp 41-42°
Boiling point: bp0.4 229°
Toxicity data: LD50 in mice (mg/10 g): 0.54 i.v.; 0.80 i.p.; 1.04 s.c.; 3.80 orally (Kasé)
Therap-Cat: Analeptic.
Keywords: Respiratory Stimulant.

Status: This monograph has been retired and is no longer subject to revision or update.