Title: Efloxate
CAS Registry Number: 119-41-5
CAS Name: [(4-Oxo-2-phenyl-4
H-1-benzopyran-7-yl)oxy]acetic acid ethyl ester
Synonyms: 7-flavone ethyl hydroxyacetate; ethyl flavon-7-yloxyacetate; ethyl 7-flavonoxyacetate; 7-flavonoxyacetic acid ethyl ester; oxyflavil
Manufacturers' Codes: Re-1-0185
Trademarks: Recordil (Recordati)
Molecular Formula: C19H16O5
Molecular Weight: 324.33
Percent Composition: C 70.36%, H 4.97%, O 24.67%
Literature References: Prepn: P. Da Re
et al., Farmaco Ed. Sci. 13, 561 (1958);
GB 803372 and
GB 824547 (1958, 1959 both to Recordati); P. Da Re, A. Colleoni,
Ann. Chim. (Rome) 49, 1632 (1959).
Properties: Crystals from 50% ethanol, mp 123-124°. Soluble in the usual organic solvents; slightly sol in water. LD50 i.p. in rats: 3200 mg/kg (Da Re).
Melting point: mp 123-124°
Toxicity data: LD50 i.p. in rats: 3200 mg/kg (Da Re)
Therap-Cat: Vasodilator (coronary).
Keywords: Vasodilator (Coronary).