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CAS No 117704-25-3 , Doramectin Search by region : China

  • Name: Doramectin
  • Synonyms: Doramectin;Avermectin A1a, 25-cyclohexyl-5-O-demethyl-25-de(1- methylpropyl)-;
  • CAS Registry Number:
  • Transport: HAZARD
  • Melting Point: 116 - 119 C
  • Density: 1.25 g/cm3
  • Refractive index: 1.579
  • Safety Statements: 33-45-60-61-36/37-26
  • Hazard Symbols: UN NO.
  • Molecular Weight: 899.11
  • InChI: InChI=1/C50H74O14/c1-27-13-12-16-34-26-57-47-42(51)30(4)21-37(50(34,47)54)48(53)60-36-22-35(63-49(25-36)20-19-29(3)45(64-49)33-14-10-9-11-15-33)18-17-28(2)44(27)61-41-24-39(56-8)46(32(6)59-41)62-40-23-38(55-7)43(52)31(5)58-40/h12-13,16-17,19-21,27,29,31-33,35-47,51-52,54H,9-11,14-15,18,22-26H2,1-8H3/b13-12+,28-17+,34-16+/t27-,29-,31-,32-,35+,36-,37-,38-,39-,40-,41-,42+,43-,44?,45-,46?,47+,49+,50+/m0/s1
  • Risk Statements: 25-50/53
  • Molecular Formula: C50H74O14
  • Molecular Structure:CAS No:117704-25-3 Doramectin

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References of Doramectin
Title: Doramectin
CAS Registry Number: 117704-25-3
CAS Name: 25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1a
Synonyms: 25-cyclohexylavermectin B1
Manufacturers' Codes: UK-67994
Trademarks: Dectomax (Pfizer)
Molecular Formula: C50H74O14
Molecular Weight: 899.11
Percent Composition: C 66.79%, H 8.30%, O 24.91%
Literature References: Mutational biosynthetic antiparasitic antibiotic structurally related to the avermectins, q.v. Isoln: S. P. Gibson et al., EP 214731; eidem, US 5089480 (1987, 1992 both to Pfizer). Mutational biosynthesis: C. J. Dutton et al., J. Antibiot. 44, 357 (1991). Pharmacokinetics and efficacy in cattle: Vet. Parasitol. 49, 1-119 (1993). Clinical evaluation as prophylactic in canine spirocercosis: E. Lavy et al., Res. Vet. Sci. 75, 217 (2003).
Properties: mp 116-119°.
Melting point: mp 116-119°
Therap-Cat-Vet: Antiparasitic.