Home > Name List By 2 > 2-[2-[acetyl(propan-2-yl)amino]ethyl]-2-(2-chlorophenyl)-4-piperidin-1- ylbutanamide

CAS No 116078-65-0 , 2-[2-[acetyl(propan-2-yl)amino]ethyl]-2-(2-chlorophenyl)-4-piperidin-1-
ylbutanamide

  • Name: 2-[2-[acetyl(propan-2-yl)amino]ethyl]-2-(2-chlorophenyl)-4-piperidin-1-
    ylbutanamide
  • Synonyms: BRN 6536016; C22H34ClN3O2; Bidisomidum [INN-Latin];2-[2-[acetyl(propan-2-yl)amino]ethyl]-2-(2-chlorophenyl)-4-piperidin-1-
    ylbutanamide; 116078-65-0;Bidisomide (+-)-; SC 40230; Bidisomida [INN-Spanish]; SC-40230;
  • CAS Registry Number:
  • Flash Point: 316.5°C
  • Boiling Point: 599.8°Cat760mmHg
  • Density: 1.124g/cm3
  • Flash Point: 316.5°C
  • Molecular Weight: 407.97726
  • InchiKey: GTEPPJFJSNSNIH-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H34ClN3O2/c1-17(2)26(18(3)27)16-12-22(21(24)28,
    19-9-5-6-10-20(19)23)11-15-25-13-7-4-8-14-25/h5-6,9-10,17H,4,7-8,
    11-16H2,1-3H3,(H2,24,28)
  • Molecular Formula: C22H34ClN3O2
  • Molecular Structure:CAS No:116078-65-0 2-[2-[acetyl(propan-2-yl)amino]ethyl]-2-(2-chlorophenyl)-4-piperidin-1-<br />ylbutanamide

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  • Bidisomide, 99%
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References of 2-[2-[acetyl(propan-2-yl)amino]ethyl]-2-(2-chlorophenyl)-4-piperidin-1-
ylbutanamide
Title: Bidisomide
CAS Registry Number: 116078-65-0
CAS Name: a-[2-[Acetyl(1-methylethyl)amino]ethyl]-a-(2-chlorophenyl)-1-piperidinebutanamide
Synonyms: (±)-a-(o-chlorophenyl)-a-[2-(N-isopropylacetamido)ethyl]-1-piperidinebutyramide
Manufacturers' Codes: SC-40230
Molecular Formula: C22H34ClN3O2
Molecular Weight: 407.98
Percent Composition: C 64.77%, H 8.40%, Cl 8.69%, N 10.30%, O 7.84%
Literature References: Sodium channel blocker. Prepn: B. N. Desai et al., EP 170901; eidem, US 4639524 (1986, 1987 both to Searle); eidem, J. Med. Chem. 31, 2158 (1988). Cardiovascular pharmacology: L. G. Frederick et al., Cardiovasc. Res. 23, 897 (1989). Electrophysiologic study: S. M. Garthwaite et al., Drug Dev. Res. 27, 329 (1992). Bioavailability and tolerability in humans: R. L. Page et al., Clin. Pharmacol. Ther. 51, 371 (1992). Clinical pharmacokinetics: C. S. Cook et al., Pharm. Res. 10, 1675 (1993).
Properties: Crystals from ethyl acetate, mp 140-141°.
Melting point: mp 140-141°
Therap-Cat: Antiarrhythmic (class I).
Keywords: Antiarrhythmic.