CAS No 1159-93-9 , 2-chloro-5-[2-(dimethylamino)ethyl]-11H-benzo[b][1,4]benzodiazepin-6-one

Name: 2-chloro-5-[2-(dimethylamino)ethyl]-11H-benzo[b][1,4]benzodiazepin-6-one
Synonyms: 5H-Dibenzo(b,e)(1,4)diazepin-11-one;2-chloro-5-[2-(dimethylamino)ethyl]-11H-benzo[b][1,4]benzodiazepin-6-one; BRN 0895864;Clobenzepamum [INN-Latin]; 10,11-dihydro-7-chloro-10-(2-(dimethylamino)ethyl)-;
CAS Registry Number:1159-93-9
Flash Point: 250.1°C
Boiling Point: 490°Cat760mmHg
Density: 1.227g/cm³
Refractive index: 1.6
Flash Point: 250.1°C
Molecular Weight: 315.79732
InchiKey: IDWVKNARDDZONS-UHFFFAOYSA-N
InChI: InChI=1S/C17H18ClN3O/c1-20(2)9-10-21-16-8-7-12(18)11-15(16)19-14-6-4-3-
5-13(14)17(21)22/h3-8,11,19H,9-10H2,1-2H3
Molecular Formula: C₁₇H₁₈ClN₃O
Molecular Structure:

Related products

Select to

          
           1159-93-9 Clobenzepam
           Clobenzepam, Min 99%
 
             Finechemie Co., Ltd. 
             
              [Manufacturer]
Tel: +86-23-99186710 
Fax: +86-23-99186729 
Address: 28th Floor Mordern Building,New-Tech Zone400020  ChongqingCHINA Chongqing,nullChina

           1159-93-9 Clobenzepam
           Clobenzepam, 99%
 
             Facus Pharmaceutical Co., Ltd. 
             
              [Manufacturer]
Tel: +86-(0)574-62378411   
Fax: +86-(0)574-62378410  
Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 
 
315800  NingboCHINA Ningbo,nullChina

           1159-93-9 CLOBENZEPAM
           
             Nanjing Chemlin Chemical Industry Co.,Ltd.
             
              [Manufacturer]
Tel:  +86 25 8369-7070/ +86 138 51816776 (Mobile)
Fax:  +86 25 8345-3275
Address: Rm.902 Longyin Plaza,
No. 217 Zhongshan Rd.
(N)Nanjing 210009,China null,nullChina

Select to

1/1

References of 2-chloro-5-[2-(dimethylamino)ethyl]-11H-benzo[b][1,4]benzodiazepin-6-one

Title: Clobenzepam
CAS Registry Number: 1159-93-9
CAS Name: 7-Chloro-10-[2-(dimethylamino)ethyl]-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
Synonyms: 7-chloro-10-(2-dimethylaminoethyl)dibenzo[b,e][1,4]diazepin-11(10H)-one; 7-chloro-10-(b-dimethylaminoethyl)-10,11-dihydro-11-oxo-5H-dibenzo[b,e][1,4]diazepine
Molecular Formula: C17H18ClN3O
Molecular Weight: 315.80
Percent Composition: C 64.66%, H 5.75%, Cl 11.23%, N 13.31%, O 5.07%
Literature References: Prepn: BE 611926 (1962 to Parke, Davis), C.A. 57, 13785a (1962); GB 961106; Schmutz, Hunziker, US 3419547 (1964, 1968 both to Wander). Pharmacology: H. Ackermann et al., Med. Exp. 6, 205 (1962); F. Hunziker et al., Arzneim.-Forsch. 13, 324 (1963).
Properties: Colorless prisms from acetone-ether, mp 165-166°. uv max (alcohol): 230 nm (32,740).
Melting point: mp 165-166°
Absorption maximum: uv max (alcohol): 230 nm (32,740)

Derivative Type: Hydrochloride
CAS Registry Number: 2726-03-6
Trademarks: Tarpan (Wander)
Molecular Formula: C17H18ClN3O.HCl
Molecular Weight: 352.26
Percent Composition: C 57.96%, H 5.44%, Cl 20.13%, N 11.93%, O 4.54%
Properties: Colorless prisms from alcohol-ether, mp 225-233°. LD50 orally in mice: 330 mg/kg (Hunziker).
Melting point: mp 225-233°
Toxicity data: LD50 orally in mice: 330 mg/kg (Hunziker)

Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Tricyclics; Other Tricyclics.

Status: This monograph has been retired and is no longer subject to revision or update.