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CAS No 114870-03-0 , Fondaparinux sodium Search by region : China

  • Name: Fondaparinux sodium
  • Synonyms: decasodium (2R,3S,4S,5R,6R)-3-[(2R,3R,4R,6R)-5-[(2R,3R,4S,5S,6S)-6-carboxylato-5-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-3-(sulfonatoamino)-6-(sulfonatooxymethyl)oxan-2-yl]oxy-3,4-dihydroxy-oxan-2-yl]oxy-3-(sulfonatoamino)-4-sulfonatooxy-6-(sulfonatooxymethyl)oxan-2-yl]oxy-4-hydroxy-6-[(2R,3S,4R,5R,6S)-4-hydroxy-6-methoxy-5-(sulfonatoamino)-2-(sulfonatooxymethyl)oxan-3-yl]oxy-5-sulfonatooxy-oxane-2-carboxylate;Fondaparinux sodium;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Flash Point: °C
  • Molecular Weight: 1728.08
  • InChI: InChI=1/C31H53N3O49S8.10Na/c1-69-27-9(33-85(48,49)50)13(37)17(6(74-27)3-71-88(57,58)59)76-31-22(83-91(66,67)68)16(40)21(24(81-31)26(43)44)79-29-10(34-86(51,52)53)19(82-90(63,64)65)18(7(75-29)4-72-89(60,61)62)77-30-15(39)14(38)20(23(80-30)25(41)42)78-28-8(32-84(45,46)47)12(36)11(35)5(73-28)2-70-87(54,55)56;;;;;;;;;;/h5-24,27-40H,2-4H2,1H3,(H,41,42)(H,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68);;;;;;;;;;/q;10*+1/p-10/t5-,6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16+,17-,18?,19-,20+,21+,22-,23+,24-,27+,28-,29-,30-,31-;;;;;;;;;;/m1........../s1
  • Molecular Formula: C31H43N3Na10O49S8
  • Molecular Structure:CAS No:114870-03-0 Fondaparinux sodium

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References of Fondaparinux sodium
Title: Fondaparinux Sodium
CAS Registry Number: 114870-03-0
CAS Name: Methyl O-2-deoxy-6-O-sulfo-2-(sulfoamino)-a-D-glucopyranosyl-(1?4)-O-b-D-glucopyranuronosyl-(1?4)-O-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-a-D-glucopyranosyl-(1?4)-O-2-O-sulfo-a-L-idopyranuronosyl(1?4)-2-deoxy-2-(sulfoamino)-a-D-glucopyranoside 6-(hydrogen sulfate) decasodium salt
Synonyms: fondaparin sodium; SR-90107A; Org-31540
Manufacturers' Codes: IC-851589
Trademarks: Arixtra (GSK)
Molecular Formula: C31H43N3Na10O49S8
Molecular Weight: 1728.08
Percent Composition: C 21.55%, H 2.51%, N 2.43%, Na 13.30%, O 45.37%, S 14.84%
Literature References: Synthetic pentasaccharide corresponding to the antithrombin binding site of heparin, q.v. Prepn: M. Petitou et al., EP 84999; eidem, US 4818816 (1983, 1989 both to Choay); M. Petitou et al., Carbohydr. Res. 167, 67 (1987). Review of pharmacology: J. M. Herbert et al., Cardiovasc. Drug Rev. 15, 1-26 (1997). Clinical pharmacokinetics: B. Boneu et al., Thromb. Haemostasis 74, 1468 (1995). Clinical trial for prevention of post-operative deep-vein thrombosis: A. G. G. Turpie et al., N. Engl. J. Med. 344, 619 (2001). Clinical comparison with enoxaparin, q.v. in treatment of established deep-vein thrombosis: H. R. Büller et al., Ann. Intern. Med. 140, 867 (2004). Review of clinical safety and efficacy: A. G. G. Turpie, Expert Opin. Drug Saf. 4, 707-721 (2005).
Properties: White powder after lyophilisation. [a]D23 +48° (c = 0.61 in water).
Optical Rotation: [a]D23 +48° (c = 0.61 in water)
Therap-Cat: Antithrombotic.
Keywords: Antithrombotic.