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CAS No 112965-21-6 , Calcipotriene

  • Name: Calcipotriene
  • Synonyms: Calcipotriene;(1S,3S,5Z)-5-[(2E)-2-[(1R,3aR,7aR)-1-[(E,2S)-5-Cyclopropyl-5-hydroxy-pent-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexane-1,3-diol;
  • CAS Registry Number:
  • Melting Point: 166-168 ºC
  • Flash Point: 250.6ºC
  • Boiling Point: 582ºCat760mmHg
  • Density: 1.12g/cm3
  • Flash Point: 250.6ºC
  • Molecular Weight: 412.61
  • InChI: InChI=1S/C27H40O3/c1-17(6-13-25(29)20-8-9-20)23-11-12-24-19(5-4-14-27(23,24)3)7-10-21-15-22(28)16-26(30)18(21)2/h6-7,10,13,17,20,22-26,28-30H,2,4-5,8-9,11-12,14-16H2,1,3H3/b13-6+,19-7+,21-10-/t17-,22-,23-,24?,25-,26+,27-/m1/s1
  • Molecular Formula: C27H40O3
  • Molecular Structure:CAS No:112965-21-6 Calcipotriene
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112965-21-6 Calcipotriol

  • India Shreeji Pharma International [Manufacturers]
  • Tel: +91-265-3019110
  • Fax: +91-265-2465036
  • Address: FF/10, Narsinghdham Complex, Sangam Chararasta, Harni Road, Vadodara, Gujarat 390018, Vadodara,GujaratIndia
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112965-21-6 Calcipotriol

  • China shanghai sphchem co.,ltd [Manufacturers]
  • Tel: +86-21-56491756 13512199871
  • Fax: 0
  • Address: NO.133, Wuye, Yangxin Road ,Shanghai China shanghai,shanghai ChinaChina
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112965-21-6 CALCIPOTRIOL

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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112965-21-6 CALCIPOTRIOL

  • United States Austin Chemical Company, Inc. [Manufacturer]
  • Tel: 847-520-9600
  • Fax: 847-520-9160
  • Address: Austin Chemical Company, Inc.
    1565 Barclay Boulevard
    Buffalo Grove, IL 60089 USA null,nullUnited States
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112965-21-6; 112828-00-9 Calcipotriol

  • United Kingdom Fine Chem Trading LTD [Manufacturers]
  • Tel: +44-079-7062-7591
  • Fax: +44-087-0705-2950
  • Address: PO Box 292, Greenford, UB6 9ZL, England London,nullUnited Kingdom
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112965-21-6 Calcipotriol

  • China Maple Chemical Co.,ltd. [Manufacturer]
  • Tel: 86-574- 87512300
  • Fax: 86-574-82095182
  • Address: No.347,Sanbei Road,Sanbei Town,Cixi ,Zhejiang,China Ningbo,ZhejiangChina
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112965-21-6 Calcipotriol

  • China Facus Pharmaceutical Co., Ltd. [Manufacturers]
  • Tel: +86-(574)-6237-8411
  • Fax: +86-(574)-6237-8410
  • Address: 24Fl, Yuanjing Building, Beilun, Ningbo, Zhejiang 315800, Ningbo,ZhejiangChina
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112965-21-6 Calcipotriol

  • United States Tecoland Corporation null
  • Tel: +1-(732)-603-9577
  • Fax: +1-(732)-906-1522
  • Address: 100 Menlo Park Drive, Suite 316, Edison, New Jersey 08837-2428, null,nullUnited States
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112965-21-6 CALCIPOTRIOL - EP

  • United States ACIC [Manufacturer]
  • Tel: 800-265-6727/ 519-751-3668
  • Fax: 519-751-1378
  • Address: 11772 West Sample Road,
    Coral Springs, Florida, 33065 USA null,nullUnited States
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112965-21-6; 112828-00-9 Calcipotriol

  • China Hangzhou VIWA Co., Ltd. [Manufacturers]
  • Tel: 0086-571-56836886, 56832058, 56836878
  • Fax: 0086-571-87175163, 87858383
  • Address: Block B, 5F, Huanglong Hengli Mansion,No.5 Huanglong Road, Hangzhou, China Hangzhou,ZhejiangChina
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References of Calcipotriene
Title: Calcipotriene
CAS Registry Number: 112965-21-6
CAS Name: (1a,3b,5Z,7E,22E,24S)-24-Cyclopropyl-9,10-secochola-5,7,10(19),22-tetraene-1,3,24-triol
Synonyms: (1S,1¢E,3R,5Z,7E,20R)-9,10-seco-20-(3¢-cyclopropyl-3¢-hydroxyprop-1¢-enyl)-1,3-dihydroxypregna-5,7,10(19)-triene; calcipotriol
Manufacturers' Codes: MC-903
Trademarks: Daivonex (Leo Pharm); Dovonex (Westwood-Squibb); Psorcutan (Schering AG)
Molecular Formula: C27H40O3
Molecular Weight: 412.60
Percent Composition: C 78.60%, H 9.77%, O 11.63%
Literature References: Vitamin D3 analog with low calcemic activity. Prepn: M. J. Calverley, E. T. Binderup, WO 8700834; eidem, US 4866048 (1987, 1989 both to Leo Pharm.); M. J. Calverley, Tetrahedron 43, 4609 (1987). Pharmacology: L. Binderup, E. Bramm, Biochem. Pharmacol. 37, 889 (1988); P. J. Marie et al., Bone 11, 171 (1990). Receptor binding: T. Valaja et al., Biochem. Pharmacol. 40, 1827 (1990). Review of clinical trials in psoriasis: D. M. Ashcroft et al., Br. Med. J. 320, 963-967 (2000).
Properties: Crystals from methyl formate, mp 166-168°. uv max (96% ethanol): 264 nm (e 17200).
Melting point: mp 166-168°
Absorption maximum: uv max (96% ethanol): 264 nm (e 17200)
Therap-Cat: Antipsoriatic.
Keywords: Antipsoriatic; Vitamin/Vitamin Source; Vitamin D.