Home > Name List By 2 > 2'H-Pregna-2,4,6-trieno[3,2-c]pyrazol-20-one,21-(acetyloxy)-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-, (11b,16a)-

CAS No 1110-40-3 , 2'H-Pregna-2,4,6-trieno[3,2-c]pyrazol-20-one,21-(acetyloxy)-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-, (11b,16a)-

  • Name: 2'H-Pregna-2,4,6-trieno[3,2-c]pyrazol-20-one,21-(acetyloxy)-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-, (11b,16a)-
  • Synonyms: Cortivasolo [DCIT]; H 3625; Cortivazolum [INN-Latin];Dilaster; Cortivazolum;2'H-Pregna-2,4,6-trieno[3,2-c]pyrazol-20-one,21-(acetyloxy)-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-, (11b,16a)-; Cortivazol [USAN:INN]; Altim; NSC 80998; Idaltim;
  • CAS Registry Number:
  • Flash Point: 368.7°C
  • Boiling Point: 686°Cat760mmHg
  • Density: 1.33g/cm3
  • Refractive index: 1.66
  • Flash Point: 368.7°C
  • EINECS: 214-175-8
  • Molecular Weight: 530.65452
  • InchiKey: RKHQGWMMUURILY-UHRZLXHJSA-N
  • InChI: InChI=1S/C32H38N2O5/c1-18-11-23-25-12-19(2)32(38,
    28(37)17-39-20(3)35)31(25,
    5)15-27(36)29(23)30(4)14-21-16-33-34(26(21)13-24(18)30)22-9-7-6-8-10-22/
    h6-11,13,16,19,23,25,27,29,36,38H,12,14-15,17H2,1-5H3/t19-,23+,25+,27+,
    29-,30+,31+,32+/m1/s1
  • Molecular Formula: C32H38N2O5
  • Molecular Structure:CAS No:1110-40-3 2'H-Pregna-2,4,6-trieno[3,2-c]pyrazol-20-one,21-(acetyloxy)-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-, (11b,16a)-

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References of 2'H-Pregna-2,4,6-trieno[3,2-c]pyrazol-20-one,21-(acetyloxy)-11,17-dihydroxy-6,16-dimethyl-2'-phenyl-, (11b,16a)-
Title: Cortivazol
CAS Registry Number: 1110-40-3
CAS Name: (11b,16a)-21-(Acetyloxy)-11,17-dihydroxy-6,16-dimethyl-2￠-phenyl-2￠H-pregna-2,4,6-trieno[3,2-c]pyrazol-20-one
Synonyms: 1,2,3,3a,3b,7,10,10a,10b,11,12,12a-dodecahydro-1,11-dihydroxy-2,5,10a,12a-tetramethyl-7-phenylcyclopenta[7,8]phenanthro[2,3-c]pyrazol-1-yl hydroxymethyl ketone acetate; 6,16a-dimethyl-11b,17a,21-trihydroxy-2￠-phenyl[3,2-c]pyrazolo-4,6-pregnadien-20-one 21-acetate
Manufacturers' Codes: MK-650; H-3625
Trademarks: Altim (Roussel Diamant); Diaster (Roussel Diamant); Dilaster (Hoechst)
Molecular Formula: C32H38N2O5
Molecular Weight: 530.65
Percent Composition: C 72.43%, H 7.22%, N 5.28%, O 15.08%
Literature References: Prepn: Fried et al., J. Am. Chem. Soc. 85, 236 (1963); Tishler et al., US 3067194 and US 3300483 (1962, l967 to Merck & Co.).
Properties: Double mp 160-165° and 229-230°; [a]D23 +14° (CHCl3). uv max (methanol): 283, 315 nm (e 15700, 19000).
Melting point: mp 160-165° and 229-230°
Optical Rotation: [a]D23 +14° (CHCl3)
Absorption maximum: uv max (methanol): 283, 315 nm (e 15700, 19000)
Therap-Cat: Glucocorticoid.
Keywords: Glucocorticoid.