CAS No 11079-53-1 , Bicyclo[3.3.1]non-3-ene-2,9-dione,4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-,(1R,5S,6R,7S)- Search by region : Germany

Name: Bicyclo[3.3.1]non-3-ene-2,9-dione,4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-,(1R,5S,6R,7S)-
Synonyms: Bicyclo[3.3.1]non-3-ene-2,9-dione,4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-,(1R,5S,6R,7S)-; Bicyclo[3.3.1]non-3-ene-2,9-dione,4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)-,[1R-(6-endo,7-exo)]-; Hyperforin; Bicyclo[3.3.1]non-3-ene-2,9-dione,4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-S-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)-,[1R-(1a,5a,6b,7a)]-;Bicyclo[3.3.1]non-3-ene-2,9-dione,4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)-,(1R,5S,6R,7S)- (9CI);
CAS Registry Number:11079-53-1
Melting Point: 79-80 deg C
Density: 1.01 g/cm³
Refractive index: 1.518
Water Solubility: Soluble in DMSO, methanol or 100% ethanol.
Molecular Weight: 536.78
InChI: InChI=1S/C35H52O4/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10/h13-15,18,26-27,37H,12,16-17,19-21H2,1-11H3/t27-,33+,34+,35-/m0/s1
Molecular Formula: C35H52 O4
Molecular Structure:

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11079-53-1 HYPERFORIN PURE

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11079-53-1 HYPERFORIN

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References of Bicyclo[3.3.1]non-3-ene-2,9-dione,4-hydroxy-6-methyl-1,3,7-tris(3-methyl-2-buten-1-yl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-penten-1-yl)-,(1R,5S,6R,7S)-

Title: Hyperforin
CAS Registry Number: 11079-53-1
CAS Name: (1R,5S,6R,7S)-4-Hydroxy-6-methyl-1,3,7-tris(3-methyl-2-butenyl)-5-(2-methyl-1-oxopropyl)-6-(4-methyl-3-pentenyl)bicyclo[3.3.1]non-3-ene-2,9-dione
Molecular Formula: C35H52O4
Molecular Weight: 536.78
Percent Composition: C 78.31%, H 9.76%, O 11.92%
Literature References: Principal acylphloroglucinol component in St. John's wort with concentrations of 2-4% in the fresh herb. Inhibits synaptosomal uptake of serotonin, norephinephrine and dopamine; thought to be responsible for the antidepressant activity of medicinal preparations of hypericum, q.v. Isoln and antibacterial activity: A. I. Gurevich et al., Antibiotiki 16, 510 (1971), C.A. 75, 95625 (1971). Improved isoln procedure: C. A. J. Erdelmeier, Pharmacopsychiatry 31, Suppl 1, 2 (1998). Structure: N. S. Bystrov et al., Tetrahedron Lett. 1975, 2791. Abs config: I. Brondz et al., Acta Chem. Scand. A37, 263 (1983). HPLC determn in plasma: J. D. Chi, M. Franklin, J. Chromatogr. B 735, 285 (1999). Series of articles on psychopharmacology and neurotransmitter reuptake inhibition: Pharmacopsychiatry 31, Suppl 1, 7-29 (1998).
Properties: mp 79-80°. [a]D18 +41° (in ethanol). pKa 4.8 (50% aq ethanol). uv max (methanol): 275.5 nm (log e 3.95). Unstable when exposed to air and light.
Melting point: mp 79-80°
pKa: pKa 4.8 (50% aq ethanol)
Optical Rotation: [a]D18 +41° (in ethanol)
Absorption maximum: uv max (methanol): 275.5 nm (log e 3.95)