Home > Name List By n > N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine

CAS No 1082-57-1 , N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine

  • Name: N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
  • Synonyms: 1H-Imidazol-2-amine; Tramazolina;Towk; 4,5-dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-; tramazoline hydrochloride; 1082-57-1;N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine;
  • CAS Registry Number:
  • Melting Point: 142-143 ºC
  • Flash Point: 167.3°C
  • Boiling Point: 353°Cat760mmHg
  • Density: 1.26
  • Refractive index: 1.673
  • Flash Point: 167.3°C
  • EINECS: 214-105-6
  • Molecular Weight: 215.29418
  • InchiKey: QQJLHRRUATVHED-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H17N3/c1-2-6-11-10(4-1)5-3-7-12(11)16-13-14-8-9-15-13/h3,5,
    7H,1-2,4,6,8-9H2,(H2,14,15,16)
  • Molecular Formula: C13H17N3
  • Molecular Structure:CAS No:1082-57-1 N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine

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References of N-(5,6,7,8-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazol-2-amine
Title: Tramazoline
CAS Registry Number: 1082-57-1
CAS Name: 4,5-Dihydro-N-(5,6,7,8-tetrahydro-1-naphthalenyl)-1H-imidazol-2-amine
Synonyms: 2-[(5,6,7,8-tetrahydro-1-naphthyl)amino]-2-imidazoline
Molecular Formula: C13H17N3
Molecular Weight: 215.29
Percent Composition: C 72.53%, H 7.96%, N 19.52%
Literature References: a-Adrenergic agonist. Prepn: Berg, DE 1191381; DE 1195323 (both 1965 to Thomae), C.A. 63, 8373c; 13274d (1965). Pharmacology and toxicity data: R. Engelhorn, H. Klupp, Arzneim.-Forsch. 12, 971 (1962). Activity studies: Sachsenr?der et al., ibid. 22, 392 (1972).
Properties: Crystals from isopropanol, mp 142-143°.
Melting point: mp 142-143°
 
Derivative Type: Hydrochloride monohydrate
CAS Registry Number: 3715-90-0
Manufacturers' Codes: KB-227
Trademarks: Biciron (Basotherm); Ellatun (Basotherm); Rhinaspray (Boehringer, Ing.); Rhinogutt (Thomae); Rhinospray (Thomae); Rinogutt (Boehringer, Ing.); Towk (Tanabe)
Molecular Formula: C13H17N3.HCl.H2O
Molecular Weight: 269.77
Percent Composition: C 57.88%, H 7.47%, N 15.58%, Cl 13.14%, O 5.93%
Properties: Crystals from alc + ether or acetone + ether, mp 172-174°. Sol in water. LD50 orally in mice: 195 mg/kg (Engelhorn, Klupp).
Melting point: mp 172-174°
Toxicity data: LD50 orally in mice: 195 mg/kg (Engelhorn, Klupp)
 
Therap-Cat: Decongestant.
Keywords: a-Adrenergic Agonist; Decongestant.