Home > Name List By other > (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl] -6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxy...

CAS No 103775-10-6 , (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]
-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid

  • Name: (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]
    -6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
  • Synonyms: Moexipril (INN); AC1L3LQP; Moexipril [INN:BAN]; Moexipril HCL; Moexiprilum;(3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]
    -6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid;Moexiprilum [INN-Latin]; 103775-10-6; Uniretic;
  • CAS Registry Number:
  • Flash Point: 382.8°C
  • Boiling Point: 709.3°Cat760mmHg
  • Density: 1.221g/cm3
  • Refractive index: 1.564
  • Flash Point: 382.8°C
  • Molecular Weight: 498.56806
  • InchiKey: UWWDHYUMIORJTA-HSQYWUDLSA-N
  • InChI: InChI=1S/C27H34N2O7/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25
    (30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32/h6-10,14-15,
    17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32)/t17-,21-,22-/m0/s1
  • Molecular Formula: C27H34N2O7
  • Molecular Structure:CAS No:103775-10-6 (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]<br />-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid

Related products

Search by region :

Select to

103775-10-6 Moexipril

Contact Supplier

103775-10-6 Moexipril

  • China Si Yi Chem-Pharm Co.,Ltd. [Manufacturers]
  • Tel: +86-28-8035 3957
  • Fax: +86-28-8035 3957
  • Address: Chengdu, Sichuan, 611130 China Chengdu,SichuanChina
Contact Supplier

Select to

5/5
Previous 1 2 3 4 5
References of (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]
-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
Title: Moexipril
CAS Registry Number: 103775-10-6
CAS Name: (3S)-2-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-3-isoquinolinecarboxylic acid
Manufacturers' Codes: RS-10085
Molecular Formula: C27H34N2O7
Molecular Weight: 498.57
Percent Composition: C 65.04%, H 6.87%, N 5.62%, O 22.46%
Literature References: Angiotensin converting enzyme (ACE) inhibitor; dimethoxy analog of quinapril, q.v. Prepn: M. L. Hoefle, S. Klutchko, EP 49605; eidem, US 4344949 (both 1982 to Warner-Lambert); S. Klutchko et al., J. Med. Chem. 29, 1953 (1986). Pharmacology: O. Edling et al., J. Pharmacol. Exp. Ther. 275, 854 (1995). GC-MS determn in plasma: W. Hammes et al., J. Chromatogr. B 670, 81 (1995). Clinical trials in hypertension: W. B. White et al., J. Hum. Hypertens. 8, 917 (1994); M. Stimpel et al., Cardiology 87, 313 (1996).
 
Derivative Type: Hydrochloride
CAS Registry Number: 82586-52-5
Manufacturers' Codes: CI-925; RS-10085-197; SPM-925
Trademarks: Fempress (Schwarz); Perdix (Schwarz); Univasc (Schwarz)
Molecular Formula: C27H34N2O7.HCl
Molecular Weight: 535.03
Percent Composition: C 60.61%, H 6.59%, N 5.24%, O 20.93%, Cl 6.63%
Properties: Crystals from ethanol + ethyl ether, mp 141-161°. [a]D23 +34.2° (c = 1.1 in ethanol).
Melting point: mp 141-161°
Optical Rotation: [a]D23 +34.2° (c = 1.1 in ethanol)
 
Derivative Type: Diacid hydrochloride
CAS Registry Number: 82586-57-0
Synonyms: Moexiprilat hydrochloride
Molecular Formula: C25H30N2O7.HCl
Molecular Weight: 506.98
Percent Composition: C 59.23%, H 6.16%, N 5.53%, O 22.09%, Cl 6.99%
Properties: Prepd as the monohydrate; crystals from THF + ethanol, mp 145-170°. [a]D23 +37.8° (c = 1.1 in methanol).
Melting point: mp 145-170°
Optical Rotation: [a]D23 +37.8° (c = 1.1 in methanol)
 
Therap-Cat: Antihypertensive.
Keywords: ACE-Inhibitor; Antihypertensive; N-Carboxyalkyl (peptide/lactam) Derivatives.