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CAS No 10040-45-6 , disodium

  • Name: disodium
  • Synonyms: [4-[pyridin-2-yl-(4-sulfonatooxyphenyl)methyl]phenyl] sulfate; Laxoberal; Picosulfate sodium; Laxidogol; Laxoberon; Guttalax; Evacuol; Neopax; Rapilax; Picosulfol;sodium picosulfate;disodium;
  • CAS Registry Number:
  • Melting Point: 272 - 275
  • Safety Statements: Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. Other experimental reproductive effects. A cathartic. When heated to decomposition it emits toxic fumes of SOx, NOx, and Na2O.
  • EINECS: 233-120-9
  • Molecular Weight: 481.407259
  • InchiKey: GOZDTZWAMGHLDY-UHFFFAOYSA-L
  • InChI: InChI=1S/C18H15NO8S2.2Na/c20-28(21,
    22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,
    24)25;;/h1-12,18H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2
  • Molecular Formula: C18H13NNa2O8S2
  • Molecular Structure:CAS No:10040-45-6 disodium

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10040-45-6 disodium

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10040-45-6 disodium

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10040-45-6 PICOSULFATE SODIUM (LAXATIVE)

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References of disodium
Title: Picosulfate Sodium
CAS Registry Number: 10040-45-6
CAS Name: 4,4￠-(2-Pyridinylmethylene)bisphenol bis(hydrogen sulfate) (ester) disodium salt
Synonyms: 4,4￠-(2-pyridylmethylene)diphenolbis(hydrogen sulfate) (ester) disodium salt; 4,4￠-(2-picolylidene)bis(phenylsulfuric acid) disodium salt; 2-picolylidenebis(p-phenyl sodium sulfate); disodium 4,4￠-disulfoxydiphenyl-(2-pyridyl)methane; picosulfol; sodium picosulfate
Trademarks: Guttalax-Fher (Boehringer, Ing., Italia); Laxoberal (Boehringer, Ing.); Laxoberon (Ferrosan); Neopax (Janssen); Pico-Salax (Ferring)
Molecular Formula: C18H13NNa2O8S2
Molecular Weight: 481.41
Percent Composition: C 44.91%, H 2.72%, N 2.91%, Na 9.55%, O 26.59%, S 13.32%
Literature References: Prepn: Pala, FR M5832 and US 3528986, US 3558643 (1968, 1970, 1971 all to Ist. de Angeli); Seeger, Machleidt, DE 1904322 (1970 to Thomae). Synthesis and physical-chemical data: Pala et al., Helv. Chim. Acta 51, 1164 (1968). Pharmacology: Pala et al., Arch. Int. Pharmacodyn. Ther. 164, 356 (1966). Metabolism: Perego et al., Arzneim.-Forsch. 19, 1889 (1969).
Properties: White crystalline solid from ethanol or methanol, mp 272- 275° (dec). uv max (H2O): 218, 262 nm (e 20450, 6075). Readily sol in water; slightly sol in alcohol. Practically insol in most organic solvents.
Melting point: mp 272- 275° (dec)
Absorption maximum: uv max (H2O): 218, 262 nm (e 20450, 6075)
Therap-Cat: Cathartic.
Keywords: Laxative/Cathartic.