Home > Name List By 1 > 1,3-dimethyl-7-[2-(pyridin-3-ylmethylamino)ethyl]purine-2,6-dione

CAS No 10001-43-1 , 1,3-dimethyl-7-[2-(pyridin-3-ylmethylamino)ethyl]purine-2,6-dione

  • Name: 1,3-dimethyl-7-[2-(pyridin-3-ylmethylamino)ethyl]purine-2,6-dione
  • Synonyms: BRN 1167438; Pimefyllin; Pimefylline [INN];1,3-dimethyl-7-[2-(pyridin-3-ylmethylamino)ethyl]purine-2,6-dione; Pimephylline;Pimefylline; Pimefilina [INN-Spanish]; ES 771; Pimefyllinum [INN-Latin];
  • CAS Registry Number:
  • Flash Point: 301.9°C
  • Boiling Point: 575.6°Cat760mmHg
  • Density: 1.37g/cm3
  • Refractive index: 1.682
  • Flash Point: 301.9°C
  • Molecular Weight: 314.34242
  • InchiKey: CDHVRXOLGDSJGX-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H18N6O2/c1-19-13-12(14(22)20(2)15(19)23)21(10-18-13)7-6-17-
    9-11-4-3-5-16-8-11/h3-5,8,10,17H,6-7,9H2,1-2H3
  • Molecular Formula: C15H18N6O2
  • Molecular Structure:CAS No:10001-43-1 1,3-dimethyl-7-[2-(pyridin-3-ylmethylamino)ethyl]purine-2,6-dione

Related products

Search by region :

Select to

10001-43-1 PIMEFYLLINE

  • United States 2A PharmaChem USA [Manufacturer]
  • Tel: 630-322-8887
  • Fax: 630-322-8885
  • Address: 2A PharmaChem USA
    5403 Patton Drive, Suite 208
    Lisle, Illinois 60532 null,nullUnited States
Contact Supplier

10001-43-1 PIMEFYLLINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of 1,3-dimethyl-7-[2-(pyridin-3-ylmethylamino)ethyl]purine-2,6-dione
Title: Pimefylline
CAS Registry Number: 10001-43-1
CAS Name: 3,7-Dihydro-1,3-dimethyl-7-[2-[(3-pyridinylmethyl)amino]ethyl]-1H-purine-2,6-dione
Synonyms: 7-[2-[(3-pyridylmethyl)amino]ethyl]theophylline; 7-(b-3￠-picolylaminoethyl)theophylline; pimephylline
Manufacturers' Codes: ES-771
Molecular Formula: C15H18N6O2
Molecular Weight: 314.34
Percent Composition: C 57.31%, H 5.77%, N 26.74%, O 10.18%
Literature References: Prepn: NL 6600250; Suter, Zutter, US 3350400 (1966, 1967 both to Eprova). Structure determn, properties and chemistry: eidem, Pharm. Acta Helv. 48, 133 (1973). Pharmacology: Ciaceri, Attaguile, Gazz. Med. Ital. 132, 36, 108 (1973). Metabolism: Pitrè, Farmaco Ed. Prat. 29, 46 (1974).
Properties: Crystals from isopropyl acetate, mp 111-112°. uv max (water): 270 nm. Readily sol in cold water, chloroform; sol in acetone, ethanol. LD50 in mice (mg/kg): 1900 orally, 402 i.v. (Suter, Zutter, 1973).
Melting point: mp 111-112°
Absorption maximum: uv max (water): 270 nm
Toxicity data: LD50 in mice (mg/kg): 1900 orally, 402 i.v. (Suter, Zutter, 1973)
 
Derivative Type: Nicotinate
CAS Registry Number: 10058-07-8
Manufacturers' Codes: ES-902
Trademarks: Teonicon (Neopharmed)
Molecular Formula: C15H18N6O2.C6H5NO2
Molecular Weight: 437.45
Percent Composition: C 57.66%, H 5.30%, N 22.41%, O 14.63%
Properties: Colorless, odorless powder from ethanol, mp 159-160°. uv max (water): 267 nm. Very sol in water (40% soln can be prepd); slightly sol in methanol; very slightly sol in acetone, chloroform. LD50 in mice (mg/kg): 2530 orally, 470 i.v. (Suter, Zutter, 1973).
Melting point: mp 159-160°
Absorption maximum: uv max (water): 267 nm
Toxicity data: LD50 in mice (mg/kg): 2530 orally, 470 i.v. (Suter, Zutter, 1973)
 
Therap-Cat: Vasodilator (coronary).
Keywords: Vasodilator (Coronary).