Home > Buy > Palonosetron Hydrochloride,

Palonosetron Hydrochloride,

  Post Date:  10 Oct 2011
  Expiry Date:  04 Oct 2012
 CAS No:  135729-62-3
  Detailed Description: Palonosetron Hydrochloride (GMP)

CAS:
135729-62-3

Introduction:
Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy -induced nausea and vomiting, Palonosetron is the only drug of its class approved for this use by the FDA .Palonosetron hydrochloride is a white to off-white crystalline powder. It is freely soluble in water, soluble in propylene glycol, and slightly soluble in ethanol and 2-propanol.

Simcere's Palonosetron Hydrochloride API:
Simcere's API and preparations of Palonosetron are both successfully passed and received SFDA GMP certification. Its brand name is Nuowei

Some inspection data
Specification CP
Properties White or off white crystalline powder
Specific Rotation -97.0o
PH 5.4
Loss on drying 0.5% max
Residue on ignition 0.1% max
Heavy metals 10 ppm max
Arsenic 1 ppm max
Total bacteria 1000 cfu/g max
Yeasts and Moulds 100 cfu/g max
Escherichia coli Not detected
Assay 99.7 %

Keyword: Palonosetron, Palonosetron Hydrochloride, 135729-62-3


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